nights thatsettle down
bedtime progesterone is used to support sleep and calmer nights while your physician adjusts dose to your cycle-timed labs.
CAPSULEprogesteronepublished clinical evidence
progesterone and estradiol
micronized progesterone, with estradiol where your panel indicates it. drawn at the same point in your cycle each month.
- what you get
- micronized progesterone, estradiol where indicated
- how you take it
- at night, through the luteal phase
- dosing
- set to your mid-luteal levels
- dispensed by
- a licensed US compounding pharmacy
- reviewed at
- three cycles, drawn at the same point
$149/mosee if you qualify
a physician decides what is right for you. if this is not a fit, your first panel is on us.
compounded to the dose your panel indicates. both are approved molecules.
3 cycles
the review window we use for a reliable hormone read
cycle-timed hormone monitoring and symptom tracking in routine care
what this does for you
a luteal phasewith support
progesterone dosed to what your mid-luteal draw actually shows, seven days after ovulation rather than on a calendar date.
hormones readat the right moment
the same cycle point every month, so a change in your numbers is a real change and not an artifact of when the blood was taken.
hormone symptoms vary widely from person to person, so we avoid one-size-fits-all promises. the plan is adjusted to your cycle-timed labs and your symptom pattern over time, then reviewed at three cycles against your own baseline.
why we measure it, and what we are reading
a prescription without a follow-up draw is a guess with a receipt. every marker below has a direction we expect and a date we check it, and all of it is read against your own baseline rather than a population range.
progesteronemonthly
drawn mid-luteal, roughly seven days after ovulation. drawn at the wrong point in the cycle, the number means nothing.
estradiolmonthly
read as a ratio against progesterone. the balance between them explains more than either value alone.
LH and FSHquarterly
rising FSH is among the earliest markers of the perimenopausal transition, often years before cycle length changes.
SHBGquarterly
determines how much of your sex hormones circulate free. it is why a normal total can sit on top of a functionally low free level.
prolactinfirst panel
a common and highly treatable cause of anovulation. if this is the finding, you need a physician rather than a prescription from us.
TSH and ferritinquarterly
thyroid disease and iron deficiency reproduce nearly every symptom of hormonal imbalance. both are excluded before anything is prescribed.
what happens, and when
before you start
a full panel timed to your cycle. if your cycles are irregular we establish ovulation timing first rather than drawing on an arbitrary day.
the full hormone panel, plus thyroid and ironcycle 1
progesterone through the luteal phase, unless your panel indicates otherwise. sleep usually changes first.
mid-luteal progesterone and estradiolcycles 2 to 3
dose adjusted to the mid-luteal levels we measure, drawn at the same cycle point each month.
progesterone, estradiol, symptom recordcycle 3
the review point. three cycles is the shortest interval that gives a reliable read on a hormone. one cycle is noise.
the full panel against your baselinethis is a fit if
- irregular cycles, difficult luteal weeks, PMDD, postpartum changes, or early perimenopause
- you have been told your labs are normal without being told what they were
- you want your hormones read at the right point in your cycle
- you can draw at the same cycle point each month
this is not for you if
- you are pregnant or actively trying to conceive
- you have a history of hormone-sensitive cancer, venous thromboembolism, or unexplained vaginal bleeding
- you smoke and are over 35, which compounds the thrombotic risk estradiol carries
- you are on hormonal contraception, which stays with the prescriber who wrote it
the detail
progesterone rises after ovulation and falls in the days before your period. that fall is what the difficult week is made of. micronized progesterone at night supports the luteal phase, and its metabolite allopregnanolone acts on GABA-A receptors. that is why sleep is usually the first thing to change. estradiol is added only where your panel shows a deficit. treating one of these without reading the other is how most prescribing in this area goes wrong.
nothing here is offered before it is measured.
start my labsall treatments
- clinical guidance on cycle-timed progesterone and estradiol interpretation in perimenopausal care.
compounded medications are not FDA-approved and are prescribed at the discretion of a licensed physician. this page is information, not medical advice. prova does not replace your primary care provider.
